This experiment was performed in order to study the effects of Haepyoyijintang on the pulmonary injury caused by SO₂.
Healthy adult male rats weighting about 250g were divided into 4 groups- the Normal group, the Control group, the group of Haepyoyijintang administration for 5 days after SO₂gas exposure (San-ple I ), and the group of Haepyoyijintang administration for 10 days before and for 5 days after SO₂gas exposure (Sample I),and the group of Haepyoyijinatang administration for 10 days before and for 5 days after SO₂gas exposure(Sample II).
The results were obtained as follows ;
1. In the total number of leucocyte, Sample I and Sample II decreased significantly compared with crotrol group.
2. In the erythrocyte sedimentation rate, Sample I and Sample II decreased significantly compared with Conrol group.
3. In the lung weight, Sample I and Sample II decreased significantly compared with Control p roup.
4. In the lung TBA level, only Sample II decreased significantly compared with Control group.
5. In the tracheal glycoprotein level, Sample I and Sample II decreased significantly compared with Control group.
According to the above results, Haepyoyijintang has significant effects on the pulmonary injury caud by SO ₂in rats.
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